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There’s nothing to making this French toast. But there is one thing that makes it exceptional: cream. This recipe cuts to the chase, forgoing spices and extracts, and focussing instead on eggs, cream and challah. You whip together the eggs and cream, which form a custardy mixture, then dip the eggy bread into this custard — make sure to gently squeeze the bread with your fingertips to draw the eggs and cream to the center — and fry them in butter. Outside is a crisp crepe-like shell. Inside, pudding. What are you waiting for? – Amanda & Merrill
Get the recipe Photo: Sarah Shatz
Source: http://www.huffingtonpost.com/food-52/leftover-bread_b_1239171.html
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Yesterday I discussed how to improve user acquisition, activation and activity by building Facebook directly into your web experience. There is of course another half to the equation: leveraging Facebook.com to expand your reach and engage your users. On-Facebook success is less product-heavy than success off-Facebook, although they both ultimately aim for the same outcome: engagement. While it is as much an art as a science, if you optimize for engagement and continually test your way across Facebook?s myriad of products ? you may well find yourself sitting alongside The Rock (Facebook?s best personality?) and Spotify (terrific example of being a platform first-mover).
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Reductions in the cost of genetic testing and improvements in what we know about what it tells us produce obvious benefits; if you know you are? likely to have some particular medical problem, you may be able to take precautions against it. But they also have at least one potential downside. The more is known about the chance of bad things happening to us, the less able we will be to insure against them.
A solution to this problem that is sometimes proposed is to permit individuals to have their genes tested but forbid insurance companies to require testing as a condition of insurance or to use the information it produces. The problem with that is adverse selection. If the customer knows his risk and the insurance company doesn’t, high risk and low risk customers are charged the same price, making insurance a good deal for the former and a bad deal for the latter. Insurance companies, realizing that most of those who choose to buy their insurance are bad risks, will charge accordingly, driving more of the low or average risk customers out of the market. In the limiting case, insurance is bought only by high risk customers, at a high risk price. A famous description of the problem is Akerlof’s article “The Market for Lemons.”
If we allow both insurance companies and their customers to make use of genetic information, then both high risk and low risk customers can buy insurance, but at different prices. The risk of having genetic variants that make you more likely to suffer some expensive medical problem is uninsurable, although you can still insure against the risk that, given those genes, the problem will actually appear.
The theoretical analysis of the problem is straightforward; interested readers can find one version in Chapter 6 of my Law’s Order. But the theory does not tell us how large the problem is. That depends on empirical facts, in particular on how much the information provided by genetic testing affects the expected cost of insuring someone.As it happens, I recently came across a datum relevant to that question, as a result of having my own genes tested by 23andMe, a company that does mail order genetic testing. It turned out that I had a genetic variant that implied a moderately increased risk of meningioma, the second most common type of brain tumor.
The information came a little late to be useful. Last summer, while I was part of a group on World of Warfare, one of the other players noticed that I had stopped responding. He called the house. My son took the call, came into my office, and found me half conscious on the floor. The diagnosis at the local hospital was meningioma, a benign (i.e. non-cancerous) tumor inside my skull but fortunately outside my brain. It was large enough to put pressure on my brain, so required surgery. I got surgery, all went well, and I am now fully recovered, aside from a visible scar and a tendency of my scalp to itch.
According to 23andMe, 35,000 Americans a year are diagnosed with meningioma, and in most cases the tumor is small enough not to require surgery. Assume that 10,000 of those, like my case, do, making the annual probability for a random American 1/30,000. Further assume that the average cost is $100,000. That’s the right order of magnitude?I saw the figures for what it cost my insurance company, but don’t have them ready to hand at the moment. The average cost to the insurance company of that particular risk is then about $3.
Finally, assume that my “moderately increased risk” means twice the average risk, which seems if anything a high guess. It follows that in a world where insurance companies had and used that data, my medical insurance would cost me, or my employer, three dollars a year more than in a world where the data was not available.
There are, of course, lots of other risks that my health insurance insures against. For some my genetics are presumably favorable, for some unfavorable. It would require much more information than I have to estimate how much the cost of insurance would vary from one person to another if all of that information was available and used. But at least the single datum I happen to have suggests that the effects might be small.
Labels: genetic testing, insurance, meningioma, tumor
Source: http://daviddfriedman.blogspot.com/2012/01/genetic-testing-and-insurance-one-datum.html
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TEHRAN (Reuters) ? Iran sent conflicting signals in a dispute with the West over its nuclear ambitions on Sunday, vowing to stop oil exports soon to “some” countries but postponing a parliamentary debate on a proposed halt to such sales to the European Union.
The Islamic Republic declared itself optimistic about a visit by U.N. nuclear experts that began on Sunday but also warned the inspectors to be “professional” or see Tehran reducing cooperation with the world body on atomic matters.
The International Atomic Energy Agency (IAEA) inspection delegation will seek to advance efforts to resolve a row about nuclear work which Iran says is for making electricity but the West suspects is aimed at seeking a nuclear weapon.
Tensions with the West rose this month when Washington and the European Union (EU) imposed the toughest sanctions yet in a drive to force Tehran to provide more information on its nuclear program. The measures take direct aim at the ability of OPEC’s second biggest oil exporter to sell its crude.
In a remark suggesting Iran would fight sanctions with sanctions, Iran’s oil minister said the Islamic state would soon stop exporting crude to “some” countries.
Rostam Qasemi did not identify the countries but was speaking less than a week after the EU’s 27 member states agreed to stop importing crude from Iran from July 1.
“Soon we will cut exporting oil to some countries,” the state news agency IRNA quoted Qasemi as saying.
Iranian lawmakers had been due to debate a bill on Sunday that could have cut off oil supplies to the EU in days, in a move calculated to hit ailing European economies before the EU-wide ban on took effect.
But Iranian MPs postponed discussing the measure.
“No such draft bill has yet been drawn up and nothing has been submitted to the parliament. What exists is a notion by the deputies which is being seriously pursued to bring it to a conclusive end,” Emad Hosseini, spokesman for parliament’s Energy Committee, told Mehr.
Iranian officials say sanctions have had no impact on the country.
“Iranian oil has its own market, even if we cut our exports to Europe,” oil minister Qasemi said.
Another lawmaker, Mohammad Karim Abedi, said the bill would oblige the government to cut Iran’s oil supplies to the European Union for five to 15 years, the semi-official Fars news agency reported.
REFINERS
By turning the sanctions back on the EU, lawmakers hope to deny the bloc a six-month window it had planned to give those of its members most dependent on Iranian oil – including some of the most economically fragile in southern Europe – to adapt.
The Mehr news agency quoted Foreign Minister Ali Akbar Salehi as saying during a trip to Ethiopia: “We are very optimistic about the outcome of the IAEA delegation’s visit to Iran … Their questions will be answered during this visit.”
“We have nothing to hide and Iran has no clandestine (nuclear) activities.”
Striking a sterner tone, Iran’s parliament speaker, Ali Larijani, warned the IAEA team to carry out a “logical, professional and technical” job or suffer the consequences.
“This visit is a test for the IAEA. The route for further cooperation will be open if the team carries out its duties professionally,” said Larijani, state media reported.
“Otherwise, if the IAEA turns into a tool (for major powers to pressure Iran), then Iran will have no choice but to consider a new framework in its ties with the agency.”
Iran’s parliament in the past has approved bills to oblige the government to review its level of cooperation with the IAEA. However, Iran’s top officials have always underlined the importance of preserving ties with the watchdog body.
Before departing from Vienna, IAEA Deputy Director General Herman Nackaerts said he hoped the Islamic state would tackle the watchdog’s concerns “regarding the possible military dimensions of Iran’s nuclear program.”
PARLIAMENT DEBATE
The head of the state-run National Iranian Oil Company (NIOC) said late on Saturday that the export embargo would hit European refiners, such as Italy’s Eni, that are owed oil from Iran as part of long-standing buy-back contracts under which they take payment for past oilfield projects in crude.
“The European companies will have to abide by the provisions of the buyback contracts,” Ahmad Qalebani told the ISNA news agency. “If they act otherwise, they will be the parties to incur the relevant losses and will subject the repatriation of their capital to problems.”
Italy’s Eni is owed $1.4-1.5 billion in oil for contracts it executed in Iran in 2000 and 2001 and has been assured by EU policymakers its buyback contracts will not be part of the European embargo, but the prospect of Iran acting first may put that into doubt.
Eni declined to comment on Sunday.
The EU accounted for 25 percent of Iranian crude oil sales in the third quarter of 2011. However, analysts say the global oil market will not be overly disrupted if parliament votes for the bill that would turn off the oil tap for Europe.
Potentially more disruptive to the world oil market and global security is the risk of Iran’s standoff with the West escalating into military conflict.
Iran has repeatedly said it could close the vital Strait of Hormuz shipping lane if sanctions succeed in preventing it from exporting crude, a move Washington said it would not tolerate.
“CONSTRUCTIVE SPIRIT”
The IAEA’s visit may be an opportunity to defuse some of the tension. Director General Yukiya Amano has called on Iran to show a “constructive spirit” and Tehran has said it is willing to discuss “any issues” of interest to the U.N. agency, including the military-linked concerns.
But Western diplomats, who have often accused Iran of using such offers of dialogue as a stalling tactic while it presses ahead with its nuclear program, say they doubt Tehran will show the kind of concrete cooperation the IAEA wants.
They say Iran may offer limited concessions and transparency to try to ease intensifying international pressure, but that this is unlikely to amount to the full cooperation required.
The outcome could determine whether Iran will face further isolation or whether there are prospects for resuming wider talks between Tehran and the major powers on the nuclear row.
Salehi said Iran “soon” would write a letter to the E.U.’s foreign policy chief Catherine Ashton to discuss “a date and venue” for fresh nuclear talks.
“Iran’s top nuclear negotiator Saeed Jalili in this letter, which may be sent in the coming days, also may mention other issues as well,” Salehi said, without elaborating.
The last round of talks in January 2011 between Jalili and Ashton, who represents major powers, failed over Iran’s refusal to halt its sensitive nuclear work.
“The talks will be successful as the other party seems interested in finding a way out of this deadlock,” Salehi said.
(Additional reporting by Hashem Kalantari, Robin Pomeroy and Hossein Jaseb in Tehran, Svetlana Kovalyova in Milan and Fredrik Dahl in Vienna; Writing by Parisa Hafezi and Robin Pomeroy; Editing by William Maclean)
Source: http://us.rd.yahoo.com/dailynews/rss/world/*http%3A//news.yahoo.com/s/nm/20120129/wl_nm/us_iran
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LONDON ? British police searched the offices of Rupert Murdoch’s British newspapers Saturday after arresting a police officer and four current and former staff of his tabloid The Sun as part of an investigation into police bribery by journalists.
The arrests spread the scandal over tabloid wrongdoing ? which has already caused the closure of one tabloid, the News of the World ? to a second Murdoch newspaper.
London’s Metropolitan Police said two men aged 48 and one aged 56 were arrested on suspicion of corruption early in the morning at homes in and around London. A 42-year-old man was detained later at a London police station.
Murdoch’s News Corp. confirmed that all four were current or former Sun employees.
A fifth man, a 29-year-old police officer, was arrested at the London station where he works.
The investigation into whether reporters illegally paid police for information is running parallel to a police inquiry into phone hacking by Murdoch’s now-defunct News of the World.
Officers were searching the men’s homes and the east London headquarters of the media mogul’s British newspapers for evidence.
Police said Saturday’s arrests were made as a result of information provided by the Management and Standards Committee of Murdoch’s News Corp.
News Corp. said it was cooperating with police.
“News Corporation made a commitment last summer that unacceptable news gathering practices by individuals in the past would not be repeated,” it said in a statement.
A dozen people have now been arrested in the bribery probe, though none has yet been charged.
They include former Rebekah Brooks, former chief executive of Murdoch’s News International, ex-News of the World editor Andy Coulson ? who is also Prime Minister David Cameron’s former communications chief ? and journalists from the News of the World and The Sun.
Two of the London police force’s top officers resigned in the wake of the revelation last July that the News of the World had eavesdropped on the cell phone voicemail messages of celebrities, athletes, politicians and even an abducted teenager in its quest for stories.
Murdoch shut down the 168-year-old tabloid, and the scandal has triggered a continuing public inquiry into media ethics and the relationship between the press, police and politicians.
An earlier police investigation failed to find evidence hacking went beyond one reporter and a private investigator, but News Corp. has now acknowledged it was much more widespread.
Last week the company agreed to pay damages to 37 hacking victims, including actor Jude Law, soccer star Ashley Cole and British politician John Prescott.
___
Jill Lawless can be reached at: http://twitter.com/JillLawless
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YAKIMA, Wash. ? In a Jan. 26 story about food labeling legislation, The Associated Press reported erroneously that Syngenta had announced plans to begin testing genetically modified wheat. Syngenta spokesman Paul Minehart said the company halted work on genetically modified wheat several years ago.
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CAIRO (AP) ? A professor from American University in Cairo says discovery of prostate cancer in a 2,200-year-old mummy indicates the disease was caused by genetics, not environment.
The genetics-environment question is key to understanding cancer.
AUC professor Salima Ikram, a member of the team that studied the mummy in Portugal for two years, said Sunday the mummy was of a man who died in his forties.
She said this was the second oldest known case of prostate cancer.
“Living conditions in ancient times were very different; there were no pollutants or modified foods, which leads us to believe that the disease is not necessarily only linked to industrial factors,” she said.
A statement from AUC says the oldest known case came from a 2,700 year-old skeleton of a king in Russia.
Associated Press
When I was a kid, I read tons of superhero comic books. I fantasized about superpowers, but the storylines about heroes with massive Achilles? heels really held my attention the most. They saved the world but had screwed up personal lives, made lots of mistakes, and often acted like complete assholes. In retrospect, I related to their flaws. And, probably not coincidentally, my favorite characters exhibited core weaknesses I had experienced: Spider-Man (immaturity), Iron Man (overconfidence/hubris), and Wolverine (rage). Ironically, when the character?s weakness comingled with the superpower, it would often spur them to succeed against impossible odds.
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OAKLAND, Calif (Reuters) ? More than 400 anti-Wall Street protesters were arrested in Oakland during a night of skirmishes in which police fired tear gas and bean bag projectiles, the city said on Sunday, marking one of the biggest mass arrests since nationwide economic protests began last year.
Earlier on Sunday, authorities had said that the arrest figure was between 200 and 300. But the Oakland emergency operations center said in a statement that revised that up to more than 400, and said that Oakland Police were expected to announce a more precise number later on Sunday.
Riot police on Saturday night fought running skirmishes with protesters, injuring three officers and at least one demonstrator.
The scuffles erupted in the afternoon as activists sought to take over a shuttered downtown convention center, sparking cat-and-mouse battles that lasted well into the night in a city that has seen tensions between police and protesters boil over repeatedly.
Oakland has become an unlikely flashpoint of the national “Occupy” protests against economic inequality that began last year in New York’s financial district and have spread to dozens of cities across the country.
The protests in most cities have been peaceful and sparked a national debate over how much of the country’s wealth is held by the richest 1 percent of the population. President Barack Obama has sought to capitalize on the attention by calling for higher taxes on the richest Americans.
Protests focused on Oakland after a former Marine, Scott Olsen, was critically injured during a demonstration in October. Protesters said he was hit in the head by a tear gas canister but authorities have never said exactly how he was hurt.
The Occupy movement appeared to lose momentum late last year as police cleared protest camps in cities across the country.
Violence erupted again in Oakland on Saturday when protesters attempted to take over the apparently empty downtown convention center to establish a new headquarters and draw attention to the problem of homelessness.
Police in riot gear moved in, firing smoke grenades, tear gas and bean-bag projectiles to drive the crowd back.
“Officers were pelted with bottles, metal pipe, rocks, spray cans, improvised explosive devices and burning flares,” the Oakland Police Department said in a statement. “Oakland Police Department deployed smoke and tear gas.”
Some activists, carrying shields made of plastic garbage cans and corrugated metal, tried to circumvent the police line, and surged toward police on another side of the building as more smoke canisters were fired.
Oakland city officials said “extremists” were fomenting the demonstrations and using the city as a playground for the movement. Protesters have accused the city of overreacting and using heavy-handed tactics.
Across the country in New York, police said four people were arrested on Saturday night after protesters clashed with police at what demonstrators had called an “OccuParty” inside an abandoned building in the borough of Brooklyn. Protesters knocked over garbage pails and hurled objects at police, slightly injuring six officers, a police spokesman said. The four people were charged with a variety of crimes including inciting a riot.
Tension was rising in Washington as well, where the National Park Service has said it will bar Occupy protesters in the nation’s capital from camping in two parks near the White House where they have been living since October.
That order, if carried out as promised on Monday, could be a blow to one of the highest-profile chapters of the movement.
(Additional reporting by Barbara Goldberg in New York and Kim Dixon and Rachelle Younglai in Washington; Editing by Greg McCune and Corrie MacLaggan)
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